I didn’t have too much trouble building a Megalopolis, although it did take a significant amount of time. I left plenty of space for industrial zones, as they are the only zone type that grows later on in the game. Residential zones on the outskirts tend to turn into slums, and commercial zones only grow so much before quitting on you. Of course, industrial zones also tend to produce a lot of crime so you have to place a significant number of police stations around them.
Once you build a Megalopolis, there tend be a lot more plane crashes. It’s a minor annoyance, but even minor annoyances can turn into bigger irritations when it happens frequently enough. When your city reaches a certain size, you can’t avoid planes hitting (usually) residential zones. It would be a frightening world indeed if planes came down on houses as frequently as they do in SimCity. Nevertheless, as far as disasters go, it’s probably the easiest to deal with. Other than that, there weren’t too many challenges in reaching 600,000 people, and I still have some space left to develop if I so desire. Technically population 600,000 is the ultimate goal in the game, and I’m pretty sure there aren’t any rewards left after that. I might develop the rest of the space anyway, just to see how far I can get.
In conclusion, I’m pretty much tired of SimCity now, and don’t think I will be revisiting it for awhile. I forgot to mention this earlier, but I played through practiced mode and finished all the scenarios again, and had trouble with Detroit and Las Vegas again (:P). I hope you enjoyed this series.